An innovative study presents sure evidence that the usage of antidepressant drugs to care for prenatal depression is normally not dangerous. It is not absolutely without has any risk sourcing factor, however. A new study has initiated no association between tricyclic or serotonin reuptake inhibitor (SRI) antidepressants and congenital or present at birth malformations or developmental delays.

On the other hand, researchers did find a noteworthy association between SRIs and premature delivery, as well as consequent lower birth weight.  "Nothing that we found would say that there is any reason for expectant mothers with depression to avoid taking antidepressants, but you do have to weigh the risk of early delivery associated with SRI antidepressants," said Gregory Simon, M.D., M.P.H., a research assistant professor of psychiatry and behavioral sciences at the University of Washington in Seattle and first author of the report. Thus Simon and his colleagues inspected hospital records of a large cross-sample of patients enclosed by a group-model health maintenance organization to make out all live births between January 1, 1986, and December 31, 1998. Pharmacy records were depicted to recognize antidepressant prescriptions filled or refilled within 270 days prior to delivery. The researchers identified 209 infants exposed to tricyclic antidepressants during pregnancy and 185 exposed to SRIs. (Only antidepressants belonging to these two drug classes were analyzed in this report.)  In the through research, the researchers studied on  gestational age, birth weight, head perimeter at birth, recognition of any major or minor deformity, motor delay, speech delay, and Apgar scores at one and five minutes as their primary outcome measures.  

In another research in Canada, researchers claim women can without dread make use of antidepressants for the duration of their first trimester devoid of fearing the drugs will increase their babies' risk of birth defects. However research panel used data from the Quebec Pregnancy Registry to investigate the records of 2,329 new mothers diagnosed with a psychiatric disorder and treated with antidepressants for at least 30 days before pregnancy. Consequently investigators found no dissimilarity in the rate of birth defects between women who used antidepressants and those who didn't use them during their first trimester.